We use Sendy for a lot of email lists. The problem we've run into with other programs is when you have a lot of names on lists you don't use that often, but the service wants to charge you per name, or per naming tier. Our CRM can only do 200 emails at a time through Google apps, so this was our solution.
We use it with Amazon's SES, so there is some setup you have to do for each email address or domain you want to send from, and the WYSIWYG editor isn't great. We're probably going to replace it with another one when we upgrade to 2.0.
If anyone here wants to discuss it, feel free to ping me on Twitter.
I tried Sendy the last time it was posted on PH. It's very DIY. I felt like I spent too much time managing the software rather than paying a little more for the ease of Mailchimp and staying focussed on business. I suppose if your entire business is newsletters, this is a viable alternative just based on price.
@joshbarkin yea this is certainly not for people that have a smaller email list. But I can see the value if you have a large list that you don't email frequently. That can get expensive to do via MailChimp. Just my two cents
Definitely very DIY with a ton of efficiency and convenience once you take the time to set-it up. The great thing is that Sendy is a self hosted application. You just need an Apache server running a Unix like operating system but almost all hosting companies support them.