I'm a big fan of what @destraynor and team at Intercom have built (we use it on Product Hunt). Segmented and one-on-one user messaging is incredibly powerful when used correctly.
We use intercom at Process Street and love it! We are not even using it to its full potential yet but have big plans :D - plus the guys are always rolling out new features to make the product even better, especially if you are a single page JS app
Replies
Product Hunt
Pitch Drone
Zoey
Ghosted.boo
Product Hunt
Process Street