Incredible book, but certainly not the "bible for startup management." Where H.O.M. is useful for startup founders: performance evaluations, 1:1s with subordinates, and methodically inspecting products for QA.
The rest of the book describes managing large teams, making high level business decisions, and in general being more effective in an interrupt-driven professional environment.
At startups, however, you (founder) have to create* the "busy" that HOM helps you navigate. You have to create* the systems from which HOM helps you squeeze more value.
Totally loved the book and it's probably one of the few books I have a physical copy ordered from Amazon. Will be better if Apple can put this title on iBooks. :)
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