How do you get up to speed with work after a 2-week break?

There's no easy way to get back on track to be honest. My strategy is to increase my catching up gradually. On my first day, I try to clean up my internal messaging channels, I don't go in-depth in the messages but rather read diagonally, to make sure there wasn't anything important, on top of that, I take customer calls if there are any, but I pay close attention to not overload myself with customer calls (they shouldn't take more than 40% of my time that day). If I still have time on the first day, then I start going through my email, starting with the very first email that I've received in this timeframe. The second day, I start with the email, my target is usually to dedicate around half of my day to email and the other half, between calls and internal meetings. With this strategy, it usually takes 3 to 4 days to recover, if you don't, don't push yourself. You'll get there and everything will be fine.